Richard Pazdur Selected Research

pembrolizumab

1/2022	FDA Approval Summary: Pembrolizumab, Atezolizumab, and Cemiplimab-rwlc as Single Agents for First-Line Treatment of Advanced/Metastatic PD-L1-High NSCLC.
1/2021	FDA Approval Summary: Pembrolizumab for the Treatment of Tumor Mutational Burden-High Solid Tumors.
1/2021	FDA Approval Summary: Pembrolizumab for the First-line Treatment of Patients with MSI-H/dMMR Advanced Unresectable or Metastatic Colorectal Carcinoma.
10/2020	FDA Approval Summary: Pembrolizumab plus Lenvatinib for Endometrial Carcinoma, a Collaborative International Review under Project Orbis.
1/2020	FDA Accelerated Approval of Pembrolizumab for Recurrent Locally Advanced or Metastatic Merkel Cell Carcinoma.
1/2019	FDA Approval Summary: Pembrolizumab for the Treatment of Microsatellite Instability-High Solid Tumors.
1/2019	FDA Approval Summary: Pembrolizumab for Recurrent Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing PD-L1.
1/2019	FDA Approval Summary: Atezolizumab or Pembrolizumab for the Treatment of Patients with Advanced Urothelial Carcinoma Ineligible for Cisplatin-Containing Chemotherapy.
1/2018	Characteristics of Real-World Metastatic Non-Small Cell Lung Cancer Patients Treated with Nivolumab and Pembrolizumab During the Year Following Approval.
1/2018	The FDA Oncology Center of Excellence and precision medicine.

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Richard Pazdur Research Topics

Disease

90	Neoplasms (Cancer) 11/2022 - 01/2002
51	Diarrhea 01/2022 - 05/2002
44	Disease Progression 11/2022 - 01/2002
43	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022 - 01/2003
42	Nausea 11/2022 - 05/2002
39	Fatigue 11/2022 - 10/2005
36	Breast Neoplasms (Breast Cancer) 10/2022 - 01/2002
27	Exanthema (Rash) 01/2022 - 10/2002
25	Vomiting 01/2022 - 05/2002
25	Neutropenia 01/2020 - 01/2005
22	Thrombocytopenia (Thrombopenia) 10/2021 - 01/2005
17	Multiple Myeloma 11/2022 - 01/2002
17	Hypertension (High Blood Pressure) 01/2022 - 12/2006
16	Constipation 01/2022 - 03/2005
15	Headache (Headaches) 11/2022 - 03/2005
15	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 03/2002
14	Anemia 11/2022 - 06/2008
14	Hemorrhage 01/2022 - 10/2002
13	Asthenia 01/2022 - 05/2006
13	Infections 01/2022 - 06/2005
12	Abdominal Pain (Pain, Abdominal) 01/2022 - 06/2007
12	Prostatic Neoplasms (Prostate Cancer) 01/2021 - 01/2002
11	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2022 - 01/2010
10	Renal Cell Carcinoma (Grawitz Tumor) 11/2022 - 12/2006
10	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2022 - 01/2002
9	Dyspnea (Shortness of Breath) 01/2022 - 06/2007
9	Carcinoma (Carcinomatosis) 01/2022 - 01/2004
9	Arthralgia (Joint Pain) 01/2022 - 03/2005
9	Alopecia (Baldness) 01/2022 - 10/2005
9	Fever (Fevers) 01/2022 - 03/2005
9	Neoplasm Metastasis (Metastasis) 07/2021 - 01/2002
9	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2020 - 09/2006
8	Edema (Dropsy) 01/2022 - 05/2002
8	Cough 01/2022 - 07/2014
8	Peripheral Nervous System Diseases (PNS Diseases) 01/2022 - 05/2006
8	Musculoskeletal Pain 01/2022 - 09/2014
8	Ovarian Neoplasms (Ovarian Cancer) 01/2021 - 10/2006
8	Proteinuria 01/2021 - 06/2007
8	Melanoma (Melanoma, Malignant) 01/2018 - 01/2012
7	Myalgia 01/2022 - 05/2002
7	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 01/2012 - 01/2002
6	Pain (Aches) 01/2022 - 07/2003
6	Hepatocellular Carcinoma (Hepatoma) 11/2021 - 01/2009
6	Lung Neoplasms (Lung Cancer) 01/2018 - 10/2014
6	Mucositis 01/2018 - 01/2007
6	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 08/2015 - 02/2008
5	Stomatitis 01/2021 - 06/2007
5	Philadelphia Chromosome 11/2018 - 06/2003
5	Dysgeusia (Parageusia) 12/2017 - 01/2007
5	Anorexia 01/2013 - 03/2005
5	Blast Crisis (Blast Phase) 01/2008 - 01/2002
4	Thyroid Neoplasms (Thyroid Cancer) 10/2022 - 12/2015

Drug/Important Bio-Agent (IBA)

63	Pharmaceutical PreparationsIBA 03/2022 - 01/2002
25	PlatinumIBA 10/2021 - 01/2003
16	ErbB Receptors (EGF Receptor)IBA 10/2022 - 08/2005
15	Hormones (Hormone)IBA 10/2022 - 01/2002
15	pembrolizumabIBA 01/2022 - 01/2016
13	TabletsIBA 01/2022 - 01/2002
13	Imatinib Mesylate (Gleevec)FDA Link 01/2012 - 01/2002
12	Biomarkers (Surrogate Marker)IBA 01/2022 - 03/2007
11	NivolumabIBA 01/2022 - 01/2016
11	Docetaxel (Taxotere)FDA Link 01/2018 - 01/2003
10	Anaplastic Lymphoma KinaseIBA 07/2021 - 04/2014
10	Trastuzumab (Herceptin)FDA Link 01/2021 - 10/2008
9	Bevacizumab (Avastin)FDA Link 01/2021 - 05/2004
9	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2019 - 01/2004
9	Irinotecan (Camptosar)FDA LinkGeneric 01/2019 - 05/2002
8	Immune Checkpoint InhibitorsIBA 01/2022 - 02/2017
8	Alanine Transaminase (SGPT)IBA 01/2021 - 10/2002
8	Fluorouracil (Carac)FDA LinkGeneric 09/2016 - 03/2002
7	Sorafenib (BAY 43-9006)FDA Link 01/2022 - 12/2006
7	atezolizumabIBA 01/2022 - 01/2017
7	Transaminases (Aminotransferases)IBA 01/2020 - 08/2007
7	Cisplatin (Platino)FDA LinkGeneric 12/2019 - 01/2004
7	Bortezomib (Velcade)FDA Link 11/2017 - 01/2003
6	IpilimumabIBA 01/2022 - 07/2017
6	CrizotinibIBA 01/2022 - 04/2014
6	Fulvestrant (Faslodex)FDA Link 11/2021 - 01/2002
6	taxaneIBA 01/2021 - 12/2004
6	Capecitabine (Xeloda)FDA Link 01/2021 - 05/2004
6	Letrozole (Femara)FDA LinkGeneric 01/2020 - 03/2002
6	Aspartate Aminotransferases (Aspartate Transaminase)IBA 08/2017 - 10/2002
5	Phosphotransferases (Kinase)IBA 01/2022 - 12/2006
5	B7-H1 AntigenIBA 01/2021 - 01/2016
5	Lipase (Acid Lipase)FDA Link 01/2021 - 12/2006
5	Cytarabine (Cytosar-U)FDA LinkGeneric 10/2019 - 06/2003
5	Tyrosine Kinase InhibitorsIBA 01/2018 - 12/2007
5	Erlotinib Hydrochloride (CP 358,774)FDA Link 07/2014 - 08/2005
5	Pemetrexed (MTA)FDA Link 01/2010 - 01/2004
4	Glucose (Dextrose)FDA LinkGeneric 11/2022 - 10/2007
4	IodineIBA 10/2022 - 12/2015
4	Chimeric Antigen ReceptorsIBA 01/2022 - 01/2018
4	Cyclin-Dependent Kinase 4IBA 11/2021 - 01/2018

Therapy/Procedure

111	Therapeutics 11/2022 - 01/2002
56	Drug Therapy (Chemotherapy) 10/2022 - 10/2002
10	Immunotherapy 11/2021 - 01/2016
6	Radiotherapy 01/2022 - 07/2003
6	Castration 01/2021 - 11/2013
5	Neoadjuvant Therapy 01/2022 - 07/2014
4	Drug Tapering 10/2021 - 09/2005